Dietary protein consumption and the risk of type 2 diabetes: A systematic review and meta-analysis of cohort studies. Consuming a supplement containing branched-chain amino acids during a resistance-training program increases lean mass, muscle strength and fat loss. Effects of branched-chain amino acids (BCAAs) on the progression of advanced liver disease: A Korean nationwide, multicenter, retrospective, observational, cohort study. Branched chain amino acids: Beyond nutrition metabolism. Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances, and energy metabolism substances. Role of specific dietary amino acids in clinical conditions. Branched-chain amino acids in health and disease: Metabolism, alterations in blood plasma, and as supplements. Is branched-chain amino acids supplementation an efficient nutritional strategy to alleviate skeletal muscle damage? A systematic review. Branched-chain amino acids and arginine improve performance in two consecutive days of simulated handball games in male and female athletes: A randomized trial. Diabetes and branched-chain amino acids: What is the link?. Branched-chain amino acid metabolism in cancer. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. ![]() Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Another 2018 review suggests that high levels of BCAAs may be a marker for heart diseases. ![]() According to a 2018 review, BCAAs are “essential nutrients for cancer growth,” and tumors use them as a source of energy. Some research has suggested a link between BCAA metabolism and cancer. According to a 2016 study, there is an association between high levels of BCAAs and nonalcoholic liver disease and liver injury. However, it is not clear whether they are involved in developing insulin resistance. Research indicates that increased BCAA levels may be markers of type 2 diabetes. Some research suggests that there may be a link between BCAAs and certain diseases, including: However, anyone who experiences serious side effects should stop taking the supplement and consult their doctor. Share on Pinterest A link may exist between high BCAA levels and type 2 diabetes.īCAA supplements are generally safe if a person follows the manufacturer’s instructions and does not exceed the maximum stated dosage. The researchers assessed muscle strength by testing each participant’s hand grip. The authors concluded that long-term BCAA supplementation has beneficial effects in people with advanced liver cirrhosis and that understanding these effects will require further research.Īnother study from 2017 also found that BCCA supplementation improved low muscle strength among people with liver cirrhosis. They use the resulting score to help determine how close a person is to having liver failure. Over 2 years, Model for End-Stage Liver Disease (MELD) test scores improved significantly among participants who consumed BCAAs, compared with those who did not.ĭoctors calculate MELD scores by measuring levels of certain substances in the blood, such as creatinine and bilirubin. For at least 6 months, each group consumed either BCAAs daily or a diet without BCAAs. In a 2017 study, researchers randomly assigned participants with advanced liver cirrhosis into groups. ![]() BCAA supplementation may benefit people with liver disease.
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